![]() The development of thrombophlebitis and pulmonary emboli during long-distance flights was reported, drawing attention to leg symptoms caused by prolonged sitting. Increased leg water content and fluid retention in subcutaneous tissue are caused due to airline boarding and long-distance bus travel. Brief leg raising may resolve leg edema and discomfort. Leg discomfort was estimated to be due to increased intra-leg fluid. Considering the changes in SWV and leg circumference, it was inferred that prolonged sitting causes an increase in intramuscular compartment pressure and intravascular blood volume, as well as an increase in water content in the leg subcutaneous tissue. Discussions: Because SWV is proportional to an increase in intramuscular compartment pressure in the lower leg, intramuscular compartment pressure increased over time with sitting and decreased with leg raising. Leg discomfort significantly increased after 120 min in both men and women. The percentage increase in lower leg circumference was significantly greater in women than in men, and it increased over time. Results: SWV was significantly greater in men than women and increased over time, and decreased with leg raising. Leg discomfort was assessed before sitting and 120 min. SWV and leg circumference was measured just after sitting, 60 min, 120 min, and after 3 min of leg raising. Methods: Twenty-one middle-aged men and 19 middle-aged women participated in the study. We evaluated shear wave velocity (SWV) of leg muscles, leg circumference, and leg discomfort associated with 2 h sitting. Introduction: Prolonged sitting causes leg discomfort.
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